Experimental autoimmune myasthenia gravis (EAMG)

The disease is induced in mice or rats by immunization with purified Torpedo acetylcholine receptor (AChR). Most animals develop the myasthenic typical  muscle weakness 4-6 weeks later.



Boneva N, Brenner T, Argov Z (2000) Gabapentin may be hazardous in myasthenia gravis. Muscle Nerve 23(8):1204-1208

Brenner T, Hamra-Amitay Y, Evron T, Boneva N, Seidman S, Soreq H (2003) The role of readthrough acetylcholinesterase in the pathophysiology of myasthenia gravis. FASEB J 17(2):214-222

Souroujon MC, Brenner T, Fuchs S (2010) Development of novel therapies for MG: Studies in animal models. Autoimmunity 43(5-6):446-460