Hadassah BrainLabs

Hadassah BrainLabs

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  • Home
  • About Us
    • Institute Profile
    • Management
    • Steering Committee
    • Scientists
      • Prof. Bernard Lerer M.D.
      • Prof. Hanna Rosenmann Ph.D.
      • Prof. Tamir Ben Hur M.D., Ph.D.
      • Dr Amit Lotan M.D.
      • Dr Tzuri Lifschytz Ph.D.
      • Dr Gilly Wolf Ph.D.
      • Dr. Dana Ekstein M.D., Ph.D.
      • Prof. Ruth Gabizon Ph.D.
      • Prof. Ronen Leker M.D.
      • Prof. Dimitrios Karussis M.D., Ph.D.
      • Prof. Adi Vaknin-Dembinsky M.D., Ph.D.
      • Prof. Talma Brenner Ph.D.
      • Prof. Haim Ovadia Ph.D.
      • Dr. Iris Lavon Ph.D.
      • Dr. Or Kakhlon Ph.D.
      • Dr. Ibrahim Kassis Ph.D.
      • Prof. Eyal Mishani Ph.D.
    • Center Infrastructure
  • Disease Models
    • Alzheimer’s Disease
      • Pharmacological Models
        • ICV Aβ -induced amnesia
        • Acetylcholine receptor antagonist-induced amnesia
      • Genetic Models
        • Amyloid (APPswe,PSEN1De9) tg- mice
        • Amyloid (5XFAD) tg-mice
    • Tauopathies
      • Tangle (htauP301S/K257T)-tg mice
    • Parkinson’s Disease
      • 6OHDA injected rats
    • ALS
      • ALS (SOD1-G93A) tg-mice
    • Myasthenia gravis
      • Experimental autoimmune myasthenia gravis (EAMG)
    • Multiple Sclerosis
      • Experimental autoimmune encephalomyelitis (EAE)
        • Acute EAE
        • Chronic EAE
        • Relapsing EAE
        • Relapsing-Progressive EAE
      • Toxic Model
    • Prion diseases
      • Transmissible model (RML PrP infected mice)
      • Prion (TgMHu2ME199K) tg-mice
    • Epilepsy
      • Pilocarpine model of chronic temporal lobe epilepsy (TLE)
    • Cerebrovascular diseases
      • Focal ischemia (craniectomy)
      • Vascular Dementia (Vascular Cognitive Impairment)
      • Focal ischemia (photothrombosis)
      • Global ischemia
      • Intracerebral hemorrhage
    • Depression
      • Surgical models
        • Olfactory bulbectomy
        • White matter lesions
      • Environmental models
        • Learned helplessness
        • Social isolation
        • Social defeat
      • Genetic models
        • Wistar Kyoto rats
    • Anxiety
      • Serotonin transporter knockout mouse
      • 5HT1A receptor knockout mouse
    • Schizophrenia
      • Acute pharmacological models of psychosis
        • MK-801 -induced PPI deficits
        • Ketamine -induced hyperlocomotion
        • Ketamine -induced stereotypic behavior
        • MK-801- induced hyperlocomotion
      • Neurodevelopmental models
        • Neurodevelopmental model of schizophrenia – transient neonatal NMDAR blockade
        • Sub-chronic juvenile MK801 model of schizophrenia
      • DISC1 mutant mice
    • Autism
      • BTBR mice
      • Juvenile BALB/c mice
      • Maternal Immune system activation
    • ADHD
      • Dopamine Transporter (DAT) Knockout (KO) Mouse
    • PTSD
      • Fear conditioning with pre-exposure
      • Predator scent model
    • OCD
      • Marble Burying and Nestlet Shredding
    • Environmental stress models
      • Social Isolation
      • Chronic Unpredictable Stress (CUS)
      • Social Defeat
    • Combined genetic-environmental models
    • Customized Models
  • Outcome Measures
    • Behavioral Assays
      • Motor Domain
        • Motor Scores
        • Clinical Scores
        • Parkinson’s Disease Scores
      • Cognitive, learning and memory domain
      • Psychosis-like Domain
      • Depressive-like domain
      • Anxiety-like Domain
      • Social Domain
      • Intellicage
    • Neuropathology
      • Cells in the CNS
        • Neurons, Astrocytes, Microglia, Oligodendrocytes
        • Blood vessels
        • Transplanted cells
        • Neurogenesis
      • Neuroinflammation
      • Neurodegeneration
        • Neurofibrillary tangles, Amyloid plaques
        • De/Myelination
        • Axonal damage
        • Prion (PrP) pathology
        • Apoptosis
    • Biochemistry
      • Proteins (soluble, resistant, phosphorylated, glycosylated)
      • Alzheimer’s disease markers; Growth factors
      • Secretases activity
    • Immunology
      • T-cell proliferation, Ab titers
      • Cytokines
      • Typing of Immune cells
    • Genetics and Molecular biology
      • Genotyping
      • Gene expression
    • Electrophysiology
      • Video EEG Monitoring
    • Brain Imaging
  • Working With Us
    • Endorsements
    • Our Added Value
    • Project Flowchart
    • Publications
  • Contact Us

Alzheimer’s Disease

Pharmacological models

  • ICV Aβ- induced amnesia
  • AChE receptor antagonist- induced amnesia

Genetic models

  • Amyloid (APPswe,PSEN1De9) tg- mice
  • Amyloid (5XFAD) tg-mice

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