Hadassah BrainLabs
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About Us
Institute Profile
Management
Steering Committee
Scientists
Prof. Bernard Lerer M.D.
Prof. Hanna Rosenmann Ph.D.
Prof. Tamir Ben Hur M.D., Ph.D.
Dr Amit Lotan M.D.
Dr Tzuri Lifschytz Ph.D.
Dr Gilly Wolf Ph.D.
Dr. Dana Ekstein M.D., Ph.D.
Prof. Ruth Gabizon Ph.D.
Prof. Ronen Leker M.D.
Prof. Dimitrios Karussis M.D., Ph.D.
Prof. Adi Vaknin-Dembinsky M.D., Ph.D.
Prof. Talma Brenner Ph.D.
Prof. Haim Ovadia Ph.D.
Dr. Iris Lavon Ph.D.
Dr. Or Kakhlon Ph.D.
Dr. Ibrahim Kassis Ph.D.
Prof. Eyal Mishani Ph.D.
Center Infrastructure
Disease Models
Alzheimer’s Disease
Pharmacological Models
ICV Aβ -induced amnesia
Acetylcholine receptor antagonist-induced amnesia
Genetic Models
Amyloid (APPswe,PSEN1De9) tg- mice
Amyloid (5XFAD) tg-mice
Tauopathies
Tangle (htauP301S/K257T)-tg mice
Parkinson’s Disease
6OHDA injected rats
ALS
ALS (SOD1-G93A) tg-mice
Myasthenia gravis
Experimental autoimmune myasthenia gravis (EAMG)
Multiple Sclerosis
Experimental autoimmune encephalomyelitis (EAE)
Acute EAE
Chronic EAE
Relapsing EAE
Relapsing-Progressive EAE
Toxic Model
Prion diseases
Transmissible model (RML PrP infected mice)
Prion (TgMHu2ME199K) tg-mice
Epilepsy
Pilocarpine model of chronic temporal lobe epilepsy (TLE)
Cerebrovascular diseases
Focal ischemia (craniectomy)
Vascular Dementia (Vascular Cognitive Impairment)
Focal ischemia (photothrombosis)
Global ischemia
Intracerebral hemorrhage
Depression
Surgical models
Olfactory bulbectomy
White matter lesions
Environmental models
Learned helplessness
Social isolation
Social defeat
Genetic models
Wistar Kyoto rats
Anxiety
Serotonin transporter knockout mouse
5HT1A receptor knockout mouse
Schizophrenia
Acute pharmacological models of psychosis
MK-801 -induced PPI deficits
Ketamine -induced hyperlocomotion
Ketamine -induced stereotypic behavior
MK-801- induced hyperlocomotion
Neurodevelopmental models
Neurodevelopmental model of schizophrenia – transient neonatal NMDAR blockade
Sub-chronic juvenile MK801 model of schizophrenia
DISC1 mutant mice
Autism
BTBR mice
Juvenile BALB/c mice
Maternal Immune system activation
ADHD
Dopamine Transporter (DAT) Knockout (KO) Mouse
PTSD
Fear conditioning with pre-exposure
Predator scent model
OCD
Marble Burying and Nestlet Shredding
Environmental stress models
Social Isolation
Chronic Unpredictable Stress (CUS)
Social Defeat
Combined genetic-environmental models
Customized Models
Outcome Measures
Behavioral Assays
Motor Domain
Motor Scores
Clinical Scores
Parkinson’s Disease Scores
Cognitive, learning and memory domain
Psychosis-like Domain
Depressive-like domain
Anxiety-like Domain
Social Domain
Intellicage
Neuropathology
Cells in the CNS
Neurons, Astrocytes, Microglia, Oligodendrocytes
Blood vessels
Transplanted cells
Neurogenesis
Neuroinflammation
Neurodegeneration
Neurofibrillary tangles, Amyloid plaques
De/Myelination
Axonal damage
Prion (PrP) pathology
Apoptosis
Biochemistry
Proteins (soluble, resistant, phosphorylated, glycosylated)
Alzheimer’s disease markers; Growth factors
Secretases activity
Immunology
T-cell proliferation, Ab titers
Cytokines
Typing of Immune cells
Genetics and Molecular biology
Genotyping
Gene expression
Electrophysiology
Video EEG Monitoring
Brain Imaging
Working With Us
Endorsements
Our Added Value
Project Flowchart
Publications
Contact Us
Combined genetic-environmental models
Available upon request