The disease is induced in mice or rats by immunization with purified Torpedo acetylcholine receptor (AChR). Most animals develop the myasthenic typical  muscle weakness 4-6 weeks later.

References

Brenner T, Hamra-Amitay Y, Evron T, Boneva N, Seidman S, Soreq H (2003) The role of readthrough acetylcholinesterase in the pathophysiology of myasthenia gravis. FASEB J 17(2):214-222

Souroujon MC, Brenner T, Fuchs S (2010) Development of novel therapies for MG: Studies in animal models. Autoimmunity 43(5-6):446-460

Gur-Wahnon D, Mizrachi T, Wald-Altman S, Al-Roof Higazi A, Brenner T (2014). Tissue plasminogen activator involvement in experimental autoimmune myasthenia gravis: aggravation and therapeutic potential.J Autoimmun.  52:36-43